Cardiogen (20mg)
Cardiogen (20mg)

$34.00

Add to cart

Cardiogen (20mg)

$34.00

Cardiogen (20mg) For Sale

Cardiogen (AEDR) is a synthetic tetrapeptide with the sequence H-Ala-Glu-Asp-Arg-OH. It functions as a bioregulator peptide, primarily targeting fibroblasts and cardiomyocytes to modulate tissue repair and cardiovascular function.

Cardiogen Peptide Description

Cardiogen is a synthetic tetrapeptide (H-Ala-Glu-Asp-Arg-OH) that has been studied for its dual role in cardiovascular repair and cellular regulation. Cardiogen targets fibroblasts—key cells in tissue repair—and cardiomyocytes to promote heart muscle regeneration while inhibiting scar tissue formation. Its molecular structure underpins interactions with cellular signaling pathways linked to oxidative stress and inflammation.

Peptide Information

Property Value
Peptide Sequence Ala-Glu-Asp-Arg
Molecular Formula C18H31N7O9
Molecular Weight 489.5 g/mol
PubChem CID 11583989
Synonyms SCHEMBL3194515

Product Usage:

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only.  This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug.

Cardiogen Research

Research suggests Cardiogen stimulates cardiac cell proliferation, inhibits fibroblast-driven scar formation, and reduces apoptosis by suppressing p53 protein expression. Investigated for applications in heart disease (e.g., heart failure, myocardial infarction) and tissue regeneration, it may also influence cancer pathways by promoting tumor cell apoptosis in sarcoma models.

Cardiogen’s Dual Mechanism in Cardiac Repair

An experimental study investigated cardiac regeneration mechanisms using Cardiogen, a synthetic tetrapeptide, in comparative analyses with 20 naturally occurring amino acids. In heart tissue cultures from rats aged 3 months (young) and 24 months (old), Cardiogen uniquely activated cardiomyocyte proliferation while suppressing apoptosis markers like p53 protein—effects not observed with individual amino acids. This dual action suggests Cardiogen operates through distinct pathways compared to standard nutrient-based approaches, combining growth stimulation with cell survival mechanisms.

Notably, age-related disparities emerged in responses to conventional amino acids: seven amino acids showed proliferative effects in young rats versus only two in older specimens. Cardiogen’s performance remained robust across both age groups, maintaining its efficacy even in aged tissue where natural regenerative capacity diminishes. These findings position the tetrapeptide as a promising candidate for addressing age-related cardiac dysfunction, particularly in elderly populations where current regenerative therapies often underperform.1

Cardiogen Modifies Tumor Growth in M-1 Sarcoma

Cardiogen peptide exhibits a tumor-modifying effect on M-1 sarcoma in senescent rats by enhancing apoptosis and inducing hemorrhagic necrosis, leading to dose-dependent inhibition of tumor growth. Cardiogen peptide injections resulted in a higher level of apoptosis in tumor cells compared to the control group, indicating its effectiveness in promoting cell death within the tumor.

The growth of M-1 sarcoma was inhibited in a dose-dependent manner following cardiogen administration. The inhibition of tumor growth was not due to a direct cytostatic effect on the tumor cells. Instead, cardiogen appears to work through a specific mechanism involving the tumor’s vascular network, leading to hemorrhagic necrosis and increased apoptosis.2

Cardiogen and Prostate Fibroblast Function

Short peptides such as T-32, T-38, and cardiogen have been shown to significantly enhance the expression of key signaling factors like CXCL12, WEDC1, and ghrelin in aging prostate fibroblasts. These factors are crucial for fibroblast differentiation and their expression decreases in senescent cultures. 

Findings suggest these peptides could reverse age-related declines in prostate fibroblast function, highlighting their potential for developing therapies to counteract prostate aging.3

Certificate of Analysis (COA) for Every Batch

A Certificate of Analysis (COA) is a document that verifies a compound’s identity, purity, and batch quality through independent laboratory testing. Every compound from BioLongevity Labs ships with a COA tied to its specific batch, so researchers can confirm exactly what they received before it enters a protocol.

Each COA reports results from third-party laboratory analysis, including:

  • High-performance liquid chromatography (HPLC) for purity, typically confirmed at 99% or higher
  • Liquid chromatography mass spectrometry (LC-MS) for molecular identity and mass confirmation
  • Sterility and endotoxin screening where applicable
  • Chemical contaminant and residual solvent checks

COAs are sourced from independent certified labs rather than in-house testing alone, giving researchers a verifiable record of molecular integrity for each batch. All compounds are supplied for research use only.

 
FAQ.

Frequently asked questions

Email:
help@biolongevitylabsusa.com
What quality testing do you provide?
Every peptide batch ships with a Certificate of Analysis from an independent, certified testing laboratory. Analysis is performed using HPLC with UV detection, paired with mass spectrometry, to confirm both purity and molecular identity before any batch is released for sale.
Each COA lists the accession number, testing dates, and your product's specific details — CAS number, lot quantity, confirmed identity, purity percentage, and physical appearance. You'll also see two charts: an HPLC chromatogram showing the purity peak, and mass spectrometry data confirming molecular weight. A signed summary table and the testing methodology are included on every report.
Most in-vitro research protocols call for 95–99%+ purity. Lower-purity compounds can introduce variables that add noise to your results and make findings harder to reproduce. Our standard catalog sits at 98%+ or 99%+ purity, verified independently on every batch.
Reconstituted peptide solutions are generally stable for several days when kept at 2–8°C. For longer-term storage, prepare small aliquots and freeze at -20°C or -80°C, and avoid repeated freeze-thaw cycles. Use sterile bacteriostatic water and aseptic technique throughout preparation and handling.
In-stock orders placed before 12 PM PT ship the same day. Domestic orders typically arrive within 3–5 business days via standard shipping, with 1–2 day expedited options available. Lyophilized peptides ship at ambient temperature in protective packaging. Orders over $400 qualify for free domestic shipping.

Yes — we ship to qualified research institutions and laboratories worldwide. International orders include a commercial invoice, Certificate of Analysis, and a research-use-only declaration. Delivery times vary by destination, and customers are responsible for any customs duties or import requirements in their jurisdiction.

Standard vial sizes range from 2mg to 20mg depending on compound, with larger formats available on select products. Volume discounts apply starting at 3 vials of the same product, scaling up from there — contact us for bulk research-lab pricing.

Because research peptides require temperature-controlled handling, we're unable to accept returns on shipped compounds once an order has left our facility. Please review your order carefully before checkout, and reach out to our support team with any questions beforehand.

Get new compound and COA alerts

New catalog additions, restocks, and testing updates — no spam.

Have more questions?

Contact our team for information about specific peptides or orders.